Lambda Light Chain

140

Specific Proteins

Lambda light chains

Fresh serum

R1 (Buffer): 1 x 50.0 mL;
R2 (Antiserum): 1 x 9.0 mL,
Ready to use

Instructions for Use  |  Safety Data Sheet

For professional in vitro diagnostic use only.

The determination of Kappa/Lambda in human serum is important for the diagnosis and subtyping of monoclonal gammopathies. Whereas polyclonal immunoglobulins (normal or enhanced concentration) exhibit both Kappa and Lambda types of light chains in a roughly constant ratio of 2:1, monoclonal immunoglobulins exhibit only one type of light chain. Increased production of monoclonal immunoglobulins or free monoclonal light chains leads to a Kappa/Lambda quotient outside the reference range indicating the existence of a monoclonal gammopathy.

Measurement of antigen-antibody reaction by the end-point method.

The reagents are stable until expiry date when kept at 2-8°C. Stability in the instrument is at least 4 weeks if contamination is avoided. Do not freeze.

Saline (9 g/L NaCl)
Protein Calibrator High, 1 mL (R1300002501)
Immunology Control Low (R1400000901)
Immunology Control High (R1400001001)