Complement C3

209

Specific Proteins

Complement C3

Fresh serum

R1 (Buffer): 1 x 50.0 mL;
R2 (Antiserum): 1 x 7.5 mL,
Ready to use

Instructions for Use  |  Safety Data Sheet

For professional in vitro diagnostic use only.

C3C is the central point of the classic and alternative complement pathway. C3C is a constituent of C5 convertase. On activation split products of C3C has important biological functions. C3b is an opsonin and involved in immune adherence. C3a is an anaphylatoxin and a chemotoxin. C3C behaves also like an acute phase protein, therefore increased levels may be found in acute inflammatory reactions. Decreased levels are reported in complex disease, recurrent immune infections with pyrogenic bacteria, various glomerulonephritides and in congenital deficiencies.

Measurement of antigen-antibody reaction by the end-point method.

The reagents are stable until expiry date when kept at 2-8°C. Stability in the instrument is at least 4 weeks if contamination is avoided. Do not freeze.

Saline (9 g/L NaCl)
Protein Calibrator High, 1 mL (R1300002501)
Immunology Control Low (R1400000901)
Immunology Control High (R1400001001)