Apolipoprotein A1
Quantitative determination of Apolipoprotein A1 (APA) in human serum by turbidimetric immunoassay.
Tests per Kit
182
Test Category
Specific Proteins
Target Analytes
Apolipoprotein A1 (Apo A1)
Sample Type
Fresh serum
Kit Components
R1 (Buffer): 1 x 50.0 mL;
R2 (Antiserum): 1 x 9.5 mL,
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Instructions for Use | Safety Data Sheet
Intended Use
For professional in vitro diagnostic use only.
Clinical Significance
Apo A1 is the main protein component of HDL (High Density Lipoprotein). Apo A1 activates lecithin cholesterol acyltransferase which catalyses the esterification of cholesterol. The resulting esterified cholesterol can then be transported to the liver, metabolised and excreted. Persons with athero-sclerotic vascular changes frequently exhibit decreased levels of Apo A1. Even if the concentrations of apolipoprotein B are normal, a decreased Apo A1 level may be a risk factor for atherosclerotic processes. Decreased levels of Apo A1 also occur in dyslipoproteinemias, acute hepatic cirrhosis and insulin-treated patients.
Test Principle
Measurement of antigen-antibody reaction by the end-point method.
Stability & Storage
The reagents are stable until expiry date when kept at 2-8°C. Stability in the instrument is at least 4 weeks if contamination is avoided. Do not freeze.
Required but Not Supplied
Saline (9 g/L NaCl)
APO A1/B Calibrator High, 1 mL (R1300001501)
APO A1/B Control, 1 mL (R1400000401)

















