β2-Microglobulin
Quantitative determination of β2-Microglobulin (BMG) in human serum and urine by turbidimetric immunoassay.
Tests per Kit
180
Test Category
Specific Proteins
Target Analytes
β2-Microglobulin
Sample Type
Fresh serum or fresh centrifuged urine
Kit Components
R1 (Buffer): 1 x 50.0 mL;
R2 (Latex): 1 x 7.5 mL,
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Instructions for Use | Safety Data Sheet
Intended Use
For professional in vitro diagnostic use only.
Clinical Significance
BMG is a low molecular weight (11,000 Daltons) protein found on the membranes of virtually all body cells. Free BMG is a product of cell breakdown. It is secreted by the renal glomeruli, then absorbed and catabolised by the renal tubular cells. Decreased glomural filtration is associated with high serum levels of BMG, whereas tubular insufficiency is associated with normal serum and high urine levels. Markedly increased cell breakdown, as in acute leukaemia, may also be associated with high serum levels.
Test Principle
Measurement of antigen-antibody reaction by the end-point method.
Stability & Storage
The reagents are stable until expiry date when kept at 2-8°C. Stability in the instrument is at least 4 weeks if contamination is avoided. Do not freeze.
Required but Not Supplied
Saline (9 g/L NaCl)
β2-Microglobulin Standard Set, 4x1 mL (R1300002601)
β2-Microglobulin Control Low (R1400000301)
β2-Microglobulin Control High (R1400001601)
Immunology Control Low (R1400000901)
Immunology Control High (R1400001001)
