α1-Antitrypsin
Quantitative determination of α1-Antitrypsin (AAT) in human serum by turbidimetric immunoassay.
Tests per Kit
175
Test Category
Specific Proteins
Target Analytes
α1-Antitrypsin
Sample Type
Fresh serum
Kit Components
R1 (Buffer): 1 x 50.0 mL;
R2 (Antiserum): 1 x 10.0 mL,
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Instructions for Use | Safety Data Sheet
Intended Use
For professional in vitro diagnostic use only.
Clinical Significance
α1-Antitrypsin is an acute phase protein. It inhibits proteinase and serine proteases. AAT has a strong binding constant for leukocyte elastase. Increased serum levels are found in: acute infection and inflammation, acute malaria, pregnancy (in 100 %), anabolic steroid therapy, advanced malignant tumours. Decreased serum levels are found in: congenital deficiencies, juvenile cirrhosis, lung emphysema, testosterone administration.
Test Principle
Measurement of antigen-antibody reaction by the end-point method.
Stability & Storage
The reagents are stable until expiry date when kept at 2-8°C. Stability in the instrument is at least 4 weeks if contamination is avoided. Do not freeze.
Required but Not Supplied
Saline (9 g/L NaCl)
Protein Calibrator High, 1 mL (R1300002501)
Immunology Control Low (R1400000901)
Immunology Control High (R1400001001)
