Rheumatoid Factor
Quantitative determination of Rheumatoid factor (RF) in human serum by turbidimetric immunoassay (Aggregated human IgG method).
Tests per Kit
65
Test Category
Specific Proteins
Target Analytes
Rheumatoid factor (RF)
Sample Type
Fresh serum
Kit Components
R1 (Buffer): 1 x 14.0 mL;
R2 (Reagent): 1 x 3.0 mL,
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Instructions for Use | Safety Data Sheet
Intended Use
For professional in vitro diagnostic use only.
Clinical Significance
The diagnosis of rheumatoid arthritis (RA) is based largely on clinical examination, but laboratory tests (e.g. RF Test) are useful to support the clinical diagnosis and to evaluate the severity and course of the disease in the individual patient. RF is a term used to describe a variety of antibodies (in most cases of the IgM type) that will react with modified human IgG (e.g. IgG in circulating immune complexes, IgG adsorbed to latex, etc.) and IgG of animal origin. RF is highly associated with rheumatoid arthritis, as high as 90 % of patients with RA have RF titers of more than 20 IU/mL.
Test Principle
Measurement of antigen-antibody reaction by the end-point method.
Stability & Storage
The reagents are stable until expiry date when kept at 2-8°C. Stability in the instrument is at least 4 weeks if contamination is avoided. Do not freeze.
Required but Not Supplied
Saline (9 g/L NaCl)
RF Calibrator High, 1 mL (R1300001901)
Immunology Control Low (R1400000901)
Immunology Control High (R1400001001)
