Iron Ferene

123

Minerals & Trace Elements

Iron

Serum, plasma (EDTA, heparin) not haemolysed

R1: 2 x 12.5 mL;
R2: 1 x 2.2 mL,
Ready to use

Instructions for Use  |  Safety Data Sheet

For professional use only.

Iron is present in biological fluids as a component of haemoglobin and myoglobin and is bound in plasma to transferrin, which acts as a transport protein. Ferritin constitutes the plasma reserve of iron and allows the regulation of the level in the plasma. Increased iron values are an indication of haemochromatosis and liver damage. Low iron levels can be caused by malabsorption anaemia as a result of gastrointestinal disorders or due to blood loss resulting from gastrointestinal injuries or major menstrual losses. For control of martial metabolism, determining transferrin and ferritin levels can provide more detailed information.

Iron in the presence of a pH 4.8 buffer system is first released from transferrin, its carrier protein, and then quantitatively reduced to the ferrous state. The ferro++ thus obtained forms with the specific complexant Ferene S {3-(2-pyridyl) -5,6-bis-[2-(5-furylsulfonic acid)]-1,2,4-triazine} a stable coloured compound, whose colour intensity is proportional to the amount of iron present in the test sample. Interference due to copper is eliminated using special reaction conditions and a specific mask.

Store at 2 - 8 °C away from direct light. When stored as described above, reagents are stable until the expiry date stated on the label. A slight variation in the composition of the reagents can occur from batch to batch, without affecting the test results. After opening, they are stable for 30 days if closed immediately and protected from contamination, evaporation, direct light and stored at the correct temperature.

Multicalibrator (R0300000006)
Normal control serum (R0400000006)
Pathological control serum (R0400000106)