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Complement C3

Complement C3

SKU: R3330000037

Quantitative determination of Complement C3 (C3C) in human serum by turbidimetric immunoassay.

  • Tests per Kit

    65

  • Test Category

    Specific Proteins

  • Target Analytes

    Complement C3

  • Sample Type

    Fresh serum

  • Kit Components

    R1 (Buffer): 1 x 14.0 mL;
    R2 (Antiserum): 1 x 2.4 mL,
    Ready to use

  • Tech Docs

    Instructions for Use  |  Safety Data Sheet

  • Intended Use

    For professional in vitro diagnostic use only.

  • Clinical Significance

    C3C is the central point of the classic and alternative complement pathway. C3C is a constituent of C5 convertase. On activation split products of C3C has important biological functions. C3b is an opsonin and involved in immune adherence. C3a is an anaphylatoxin and a chemotoxin. C3C behaves also like an acute phase protein, therefore increased levels may be found in acute inflammatory reactions. Decreased levels are reported in complex disease, recurrent immune infections with pyrogenic bacteria, various glomerulonephritides and in congenital deficiencies.

  • Test Principle

    Measurement of antigen-antibody reaction by the end-point method.

  • Stability & Storage

    The reagents are stable until expiry date when kept at 2-8°C. Stability in the instrument is at least 4 weeks if contamination is avoided. Do not freeze.

  • Required but Not Supplied

    Saline (9 g/L NaCl)
    Protein Calibrator High, 1 mL (R1300002501)
    Immunology Control Low (R1400000901)
    Immunology Control High (R1400001001)

Clinical Area
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