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Pancreatic Elastase

Pancreatic Elastase

SKU: R3330000099

Pancreatic Elastase a latex turbidimetric assay for the quantitative detection of Pancreatic Elastase in human solid stool samples and is intended for use on the IVD analyser.

  • Tests per Kit

    100

  • Test Category

    Specific Proteins

  • Target Analytes

    Human pancreatic elastase (faecal)

  • Sample Type

    Human stool

  • Kit Components

    R1: 1 x 16.5 mL;
    R2: 1 x 2.4 mL,
    Ready to use

  • Tech Docs

    Instructions for Use  |  Safety Data Sheet

  • Intended Use

    For professional in vitro diagnostic use only.

  • Clinical Significance

    Exocrine pancreatic insufficiency (IPE) is one of the main complications in pancreas illness. It is due to the inability of the pancreas to synthesise this enzyme in the required amount. Pancreatic elastase E1 is produced in the acinar cells of the pancreas. This enzyme is involved in food digestion, and its value is clinically relevant. Human pancreatic elastase 1 (E1) remains undegraded during intestinal tract, becoming in the perfect marker to determine IPE in stool samples

  • Test Principle

    Pancreatic Pancreatic Elastase latex turbidimetric assay is based on agglutination reactions. These involve in vitro aggregation of microscopic latex particles. This aggregation consists in the specific reaction between antigen and monoclonal antibodies, antigen contained in the sample and the antibodies anti-antigen coated on polystyrene latex particles. The sample is mixed with a suspension containing antibodies against the antigen bound to latex particles. If antigen is present in the sample, it will react with the antibodies and form an aggregate. If no antigen is present in the sample the mixture will keep its appearance as a smooth suspension. Such turbidity is measured as an increase in absorbance at the determinate wave and is proportional to the quantity of antigen contained in the sample.

  • Stability & Storage

    The reagents are stable until expiry date on the label when stored at 2-8°C. DO NOT FREEZE After opening the reagents are stable for 1 month at 2-8°C.

  • Required but Not Supplied

    Standard Set Pancreatic elastase (R3330000101)
    Control Set Pancreatic Elastase (R3330000100)

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