Antithrombin III

65

Specific Proteins

Antithrombin III (AT III)

Fresh plasma

R1 (Buffer): 1 x 15.4 mL;
R2 (Antiserum): 1 x 2.4 mL,
Ready to use

Instructions for Use  |  Safety Data Sheet

For professional in vitro diagnostic use only.

AT3 is an inhibitor of thrombin, Factor Xa or Factor VIIa. There is more AT3 in blood than prothrombin; blood is able to clot only because the reaction of the inhibitor with thrombin is much slower than the action of thrombin on fibrinogen. The reactivity of AT3 is regulated by combination with its activator heparin. Decreased levels of AT3 are found in nephrotic syndrome, DIC, deep vein thrombosis, hypercoagulability syndrome, oral contraceptives, pulmonary embolism, direct hepatotoxicity, extra-corporeal circulation and L-asparginase administration.

Measurement of antigen-antibody reaction by the end-point method.

The reagents are stable until expiry date when kept at 2-8°C. Stability in the instrument is at least 4 weeks if contamination is avoided. Do not freeze.

Saline (9 g/L NaCl)
Protein Calibrator High, 1 mL (R1300002501)
Immunology Control Low (R1400000901)
Immunology Control High (R1400001001)