ALP – DEA

200

Enzymes

Alkaline phosphatase (ALP)

Use serum or plasma containing heparin or EDTA

R1: 3 x 14 mL;
R2: 1 x 10.5 mL,
Ready to use

Instructions for Use  |  Safety Data Sheet

For professional use only.

Alkaline phosphatase (ALP) is an enzyme that reacts optimally to alkaline pH. It is present in blood in numerous forms which come mainly from bone and liver, but also from other tissues such as kidneys, placenta, testicles, and lung tissue, as well as from the presence of tumours. Physiological increases occur during phases of bone growth in children and in pregnancy, which pathological increases are largely associated with hepatobiliary and bone disorders. In terms of hepatobiliary disorders, elevated activity is also observable in infectious hepatitis. The bone disorders that cause an increase in ALP activity are osteoblastic, such as Paget’s disease, osteomalacia (rickets), bone metastases and hyper-para-thyroidism.

P – nitrophenylphosphate + H2O --(AP)--> phosphate + p-nitrophenol

Store at 2 - 8°C and protect from direct light. When correctly stored, the reagents are stable up to the expiry date reported on the label. A slight variation in the composition of the reagents may occur between batches, but this has no effect on the test results. The reagents are liquid, ready to use. The solutions must be limpid with no evident precipitate. Pay attention to avoid bacterial contamination during use. The stability of the reagents are 30 days if closed, stored at 2 - 8°C and protect from direct light.

Multicalibrator (R0300000006)
Normal control serum (R0400000006)
Pathological control serum (R0400000106)